DNA methylation
Base-resolution maps of 5mC and 5hmC across tissues, ages, and exposures.
Bisulfite · Enzymatic · Long-read
Founded 2026 · A multi-institution research network
Advancing epigenetics research across the American Southwest.
The Southwest Epigenetics Consortium connects research institutions across the American Southwest. Members share sequencing and methylation cores, contribute to shared datasets, and work to shared protocols and standards maintained by the network.
Why a consortium
Infrastructure most labs cannot build alone.
High-throughput epigenomics is expensive and methodologically demanding. The consortium pools instruments, data, and expertise so member labs can work at a scale and standard that would be out of reach individually. Results return to a shared, open record.
01 — Infrastructure
Shared platforms
Pooling sequencing and methylation capacity so member labs can reach instruments and methods beyond their own.
02 — Data
Shared data standards
Common formats and quality standards so epigenome data can be compared, combined, and reused across member labs.
03 — People
Training & community
Shared protocols, method workshops, and training to support early-career researchers across the network.
—Member institutions
—Researchers in the network
—Shared core facilities
—Member publications
Research areas
Six areas of active research.
Member labs collaborate across six areas of epigenetics that cover molecular mechanism, clinical translation, and population health. Many projects draw on the shared cores.
RNA methylation
m6A, m5C, and 5hmC on RNA — writers, readers, and MeRIP/m6A-seq.
m6A · m5C · Epitranscriptome
Chromatin & histone marks
ATAC, ChIP, and CUT&RUN profiling of the regulatory landscape.
Accessibility · Modifications
Single-cell epigenomics
Cell-type-specific regulation resolved at single-nucleus resolution.
scATAC · snmC · Multiome
Cancer epigenetics
Methylation signatures for early detection, subtyping, and minimal residual disease.
Liquid biopsy · cfDNA
Computational epigenomics
Shared pipelines, aging clocks, and models built for reproducible analysis.
Pipelines · Aging clocks · ML
Resources & learning
Shared resources, maintained by the network.
Protocols, data standards, and training materials are written and kept current by member labs, and available to every group in the network.
Wet-lab protocols
Vetted, versioned bench protocols for methylation and chromatin assays.
Data standards
Metadata schemas and QC thresholds that keep datasets comparable.
Webinars & recordings
Monthly methods seminars and the annual Southwest Epigenetics Meeting.
Fellowships & training
Funded early-career fellowships and cross-lab rotations across the network.
Membership
Member institutions.
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Founding member institutions will be announced soon.
Sponsors & partners
Supported by partners in genomics and epigenetics.
These companies support the consortium's meetings, training programs, and shared platforms.
10x Genomics
Illumina
Element Biosciences
Roche
Diagenode
Active Motif
Dovetail Genomics
Arima Genomics
Hamilton
Corning
Membership
Bring your lab into the network.
Institutions, core facilities, and individual labs across the Southwest are eligible to join. Members share infrastructure, contribute to shared datasets, and help set the network's standards and priorities.